Humanised Mouse Models for Immuno-Oncology: Infectious and Inflammatory Diseases

Service description

This service provides customised preclinical studies using CD34+and PBMC humanised mouse models to evaluate innovative therapies in immuno-oncology, infectious, and inflammatory disease areas. The target audiences are biotech and pharmaceutical SMEs developing biologics, cell therapies, antibodies, and small molecules. The goal is to assess efficacy, safety, mechanism of action, and human immune responses in translational models. Activities cover study design, humanisation/engraftment, treatment administration, longitudinal monitoring, immune profiling (e.g., flow cytometry, cytokines), histopathology, data analysis andreporting. The expected outcomes of the service are decision-grade evidence for candidate selection and progression. Implementation is done in-house by TCS scientific experts (immunology, virology, inflammation), with full oversight and a complete study data package delivered to the beneficiary. The typical duration of the service is 8–12 weeks, depending on study design and endpoints.

Sector

Biotechnology

Technology Readiness Level

TRL 4 – Technology validated in lab

TRL 5 – Technology validated in relevant environment

TRL 6 – Technology demonstrated in relevant environment

Financial requirements

Price starting from €1600/mouse. Pricing per mouse, including study design, experimental work in vivo and in vitro, data analysis, and reporting, is tailored based on the specific details, mouse model selected, and scope/duration of the requested project.

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What is the challenge you want to overcome with this service?

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Why do you need this IP & Legal service?

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Why do you need this Prototyping & PoC service?

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EIC ACCESS+ Co-funding

Is this the service you are looking for? If so, you can apply to the service through EIC ACCESS+! Eligible applicants can also get co-funding through the EIC ACCESS+ initiative. Find out more on the project webiste.

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