The ENRICHers Collaborative Soft-landing Hubs in North America (USA and Canada) provide specialised support for global research and innovation actors (especially from Europe and associated countries) seeking to expand into specific industries or technology sectors. These hubs are deeply integrated with local and regional ecosystems, connecting these international companies/stakeholders to key innovation networks. By leveraging partnerships with R-1 Universities, the hubs facilitate opportunities for research-driven innovation, technology and business collaboration, commercialisation and funding. They enable access to cutting-edge research, in silico/vitro/vivo studies, proofs of concept (PoC), pilots, sales and business development programmes, and capital, while helping international players navigate the North American market. The hubs support connections with investors, industry partners, and local government resources, creating a comprehensive platform for growth and expansion. Whether the purpose is product validation/launch or strategic partnership, or access to funding, the ENRICHers hubs are designed to accelerate success in North America’s dynamic innovation and uniquely scalable landscape. The ENRICH (The European Network of Research and Innovation Centres and Hubs) global network was initially funded by the European Commission through Horizon 2020. The ENRICH in the USA initiative started in April 2017.