Chemical synthesis scale-up

Roka Furadada

Spain

Service ID:

EP303S2
Service description

The service provides comprehensive support for scaling up the production of chemical compounds, bridging the gap between lab-scale and larger-scale synthesis. The duration is flexible, determined by the initial production process development stage and the specific chemical compounds involved. Potential beneficiaries are projects in biology, chemistry, and technology fields that require chemical synthesis. We support everything from gram-scale for initial tests to multi-kilogram pilot production for pre-industrialisation. Our goal is to facilitate the efficient transition of chemical production from laboratory to larger scales, meeting the specific needs of the project. The service comprises three distinct phases. Phase 1: Synthetic route evaluation: We assess the provided synthetic protocol for scalability and propose alternatives if needed. Phase 2: Laboratory validation: The selected route is tested at a small scale and assessed for scalability. Phase 3: Desired scale production: Production is performed at the required scale using the validated route, and the obtained product is delivered. The configuration of the project phases is tailored to specific needs. While phase 1 is always included, phases 2 and 3 depend on project requirements and mutual agreement. Therefore, service outcomes are custom-made to each project, extending from a synthetic route evaluation report all the way to product delivery at a kilogram scale. Our approach is flexible, incorporating regular progress reviews and client feedback to guarantee alignment with the final product's objectives.

Sector
Biotechnology
Health and medical care
Pharmaceuticals
Technology Readiness Level
TRL 4 – Technology validated in lab
TRL 5 – Technology validated in relevant environment
TRL 6 – Technology demonstrated in relevant environment
Financial requirements

Application assessment and cosmetic ingredient efficacy: From €30,000 per ingredient with a basic cosmetic efficacy testing package. 
Galenic formulation of cosmetic products: From €8,000 including 5 prototypes (depending on formula complexity). 
Ingredient encapsulation service: Starting from €5,000 per week.

Disclaimer related to service

The project owner is responsible for delivering the analytical methods required to assess product quality. Our service does not include the development or validation of these methods.

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